International Symposium
Modeling and Simulation of the Cardiovascular System
Internationales Wissenschaftsforum Heidelberg (IWH)

February 10-12, 2014
Heidelberg University
Photograph by barnynz from flickr, published under a Creative Commons License.

Modeling and Simulation of the Cardiovascular System

Date:
February 10-12, 2014
Location:
Heidelberg University
Internationales Wissenschaftsforum Heidelberg (IWH)
Hauptstraße 242
69117 Heidelberg
(see Venue for more information)

Organizers

Willi Jäger (jaeger@iwr.uni-heidelberg.de)
Thomas Richter (thomas.richter@iwr.uni-heidelberg.de)

Sponsors

Center for Modelling and Simulation in the Biosciences - BIOMS
MAThematics Center Heidelberg (MATCH)
Interdisciplinary Center for Scientific Computing (IWR)
Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS MathComp)

Aims

Discussion of topical challenges to mathematical modeling and simulation of the cardiovascular system with focus on the following subjects:

Modeling, Analysis

  • Biomechanical interaction of blood flow with the vessel wall and tissue reactions and transport processes in blood flow and the vessel wall
  • Mechanics of the vessel walls including information on microstructures
  • Deposition and chemical processes and their influence on the vessel wall
  • Thrombus and plaque formation
  • Vessel occlusion and infarcts
  • Methods and techniques for calibration and validation based on medical data

Numerical methods and simulation:

  • Methods for long time processes
  • Simulations of fluid-structure interaction and related free boundary problems
  • Methods for processes with large deformations
  • Report and discussion of simulations results and their medical implications

Structure of the Symposium:

The Symposium will take place at a small meeting center in the Old Town of Heidelberg, belonging to the University. The program of the Symposium will provide enough time for discussion and co-operation. Therefore the number and the time for lectures will be limited. There will be invited lectures and lectures selected from the offers of interested participants. Expected participants are experts and students from Mathematical Modeling, Analysis, Numerics and Medicine.

Schedule

The schedule is subject to change.

Sunday 09/02/2014

Evening
Reception and Cold Buffet

Monday 10/02/2014

09.00 – 10.00
Registration and Coffee
10.00 – 10.15
Welcome
10.15 – 11.00
Cardiovascular Mechanics: Perspectives and Challenges Abstract Gerhard Holzapfel, Graz University of Technology
11.00 – 11.45
(to be announced) Abstract Jeremi Mizerski, ICM Warsaw
11.45 – 12.30
Active contraction of the cardiac ventricle and distortion of the microstructural architecture Abstract Davide Ambrosi, Politecnico di Milano
12.30 – 13.30
Lunch
13.30 – 14.00
Pathophysiology and state-of-the-art treatment of carotid stenosis Michael Hennerici, Neurologische Universitätsklinik Mannheim
14.00 – 14.30
Carotid stenosis - mechanical and hemodynamic factors in assessment of plaque vulnerability and in new treatment strategies Stephen Meairs, Neurologische Universitätsklinik Mannheim
14.30 – 15.00
Platelet deposition in non-parallel flow. Influence of shear stress, surface reactivity, and thrombus growth. Abstract Frederic Weller, Hochschule Esslingen
15.00 – 15.30
Coffee
15.30 – 16.00
Mathematical Modeling and Simulation of the Evolution of Plaques in Blood Vessels Abstract Yifan Yang, Universität Heidelberg
16.00 – 16.30
Multiscale modeling of the influence of chemical factors on the permeability of the endothelium Abstract Maria Neuss-Radu, Universität Erlangen
16.30 – 17.00
Pharmacokinetic/Pharmacodynamic modeling of intraarterial nimodipine therapy in cerebral vasospasm Abstract Fatih Seker, Universität Heidelberg
17.00 – 17.30
Discussion
18.30
Dinner

Tuesday 11/02/2014

09.00 – 09.45
Approaches to modelling vascular remodelling and adaptation in biological tissues Abstract Helen Byrne, University of Oxford
09.45 – 10.30
The role of geometric randomness in the mathematical modelling of angiogenesis Abstract Vincenzo Capasso, University of Milano and Carlos III University, Madrid
10.30 – 11:00
Coffee
11.00 – 11.45
Reduced Order Modeling for the Cardiovascular System Abstract Jean-Frederic Gerbeau, INRIA, Paris
11.45 – 12.30
Numerical concepts for solid growth and reaction-induced boundary movements in blood vessels Abstract Thomas Wick, University of Texas, Austin
12.30 – 13.30
Lunch
13.30 – 14.00
Multiscale Modeling of the human cardiovascular system Abstract Natalya Kizilova, Kharkov National University, Ukraine
14.00 – 14.30
Haemodynamics of cerebrovascular anomalies: AVM and AA Abstract Alexander Khe, Lavrentyev Institute of Hydrodynamics, Novosibirsk State University
14.30 – 15.00
Kinematic splitting method for fluid-structure interaction problems in hemodynamics Abstract Anna Hundertmark-Zauskova, Universität Mainz
15.00 – 15.30
Coffee
15.30 – 16.00
Improving blood flow modeling with boundary control Abstract Jorge Tiago, Instituto Superior Tecnico, Lisboa
16.00 – 16.30
High-Performance Computing based Numerical Simulations for Cognition-Guided Surgery Abstract Nicolai Schoch, Jonas Kratzke, Universität Heidelberg
16.30 – 17.00
Discussion
18.30
Dinner

Wednesday 12/02/2014

09.00 – 10.00
Intracranial aneurysm: a challenge for mathematical modeling, analysis and computations Abstract Marek Capek, Jaroslav Hron, Josef Malek, Helena Svihlova, Charles University in Prague
10.00 – 10.30
Mathematical modelling and simulations of brain cell swelling under ischaemic conditions Abstract Valeria Malieva
10.30 – 11.00
Coffee
11.00 – 11.30
Numerical simulation of blood flow in the vascular network with pathologies or implants Abstract Tatiana Dobroserdova, Moscow State University
11.30 – 12.30
Final Discussion Willi Jäger, Jeremi Mizerski, Thomas Richter
12.30 – 13:30
Lunch / Ending

Venue

The symposium takes place at the Internationales Wissenschaftsforum Heidelberg (IWH), the conference center of Heidelberg University, located in the old town of Heidelberg. You can find instructions on how to get to the IWH by car or railway on their website.

Address:
Heidelberg University
Internationales Wissenschaftsforum Heidelberg (IWH)
Hauptstraße 242
69117 Heidelberg

Preliminary list of Participants

Registration

Please register by Email to (thomas.richter@iwr.uni-heidelberg.de) not later than January 17th. Please include date of arrival and departure.

Sponsors

This symposium is sponsored by